Table of Contents
- 1 Is clopidogrel better than aspirin?
- 2 How much stronger is clopidogrel than aspirin?
- 3 Is it safe to take clopidogrel long term?
- 4 What is the major side effect of clopidogrel?
- 5 What are the advantages of clopidogrel?
- 6 Is clopidogrel a blood thinner?
- 7 Does clopidogrel with aspirin lower mortality for acute STEMI?
- 8 Does clopidogrel interact with Celebrex?
Is clopidogrel better than aspirin?
Clopidogrel is another guideline‐recommended antiplatelet agent21 and has been shown to be superior to aspirin in preventing composite vascular events and reducing hemorrhagic complications in a randomized controlled trial, CAPRIE (Clopidogrel versus Aspirin in Patients at Risk of Ischaemic Events).
Can you take aspirin instead of clopidogrel?
Aspirin combined with the antiplatelet drug clopidogrel is no better than aspirin alone for stroke prevention in people with a history of lacunar strokes, and the combination carries a greater risk of gastrointestinal bleeding, according to results of a trial funded by the National Institutes of Health.
How much stronger is clopidogrel than aspirin?
The CAPRIE trial reported that patients treated with clopidogrel had lower risk of composite vascular events (ischemic stroke, AMI, or death) than aspirin (5.32\% vs 5.83\%), with a relative risk reduction (RRR) of 8.7\% in favor of clopidogrel (95\% CI = 0.3–16.5, p 0.043).
Why is clopidogrel and aspirin used together?
The combination of clopidogrel and aspirin may lower the risk for major ischemic events among patients with minor ischemic stroke or high-risk transient ischemic attack compared with aspirin alone, according to results of the POINT study.
Is it safe to take clopidogrel long term?
Take as directed Clopidogrel oral tablet is used for long-term treatment. It comes with serious risks if you don’t take it as prescribed. If you stop taking the drug or don’t take it at all: You increase your risk of heart attack or stroke. These conditions can be fatal.
How good is clopidogrel?
Clopidogrel has an average rating of 7.1 out of 10 from a total of 79 ratings on Drugs.com. 63\% of reviewers reported a positive effect, while 22\% reported a negative effect.
What is the major side effect of clopidogrel?
Easy bleeding/bruising, stomach upset/pain, diarrhea, and constipation may occur. If any of these effects persist or worsen, tell your doctor or pharmacist promptly. Remember that this medication has been prescribed because your doctor has judged that the benefit to you is greater than the risk of side effects.
What is the safest blood thinning medication?
Safer Blood-Thinning Drugs to Prevent Stroke The newer medications are Pradaxa (dabigatran), Xarelto (rivaroxaban), Eliquis (apixaban), and most recently Savaysa (edoxaban) — which work by preventing pooled blood in the heart from clotting. Unlike warfarin, the newer drugs are safer and easier for patients to use.
What are the advantages of clopidogrel?
Clopidogrel is used to prevent heart attacks and strokes in persons with heart disease (recent heart attack), recent stroke, or blood circulation disease (peripheral vascular disease).
What are the side effects of clopidogrel 75 mg?
Clopidogrel may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:
- excessive tiredness.
- headache.
- dizziness.
- nausea.
- vomiting.
- stomach pain.
- diarrhea.
- nosebleed.
Is clopidogrel a blood thinner?
Clopidogrel is an antiplatelet blood-thinning medicine that may help prevent future heart attacks, strokes, and other clot-related diseases in patients who have already had a heart attack, stroke, or have certain cardiovascular conditions.
How long can you stay on clopidogrel?
Clopidogrel and low-dose aspirin The key question for your doctor is whether the benefits outweigh the extra risk. This combination treatment is prescribed for a limited period of time, usually up to a maximum of 12 months.
Does clopidogrel with aspirin lower mortality for acute STEMI?
CLARITY-TIMI 28 and COMMIT/CCS-2 demonstrate that the addition of clopidogrel to aspirin in patients with STEMI both improves infarct-related artery patency and reduces ischaemic complications including mortality. The benefit was consistent across a broad range of subgroups based on age, gender, use and type of fibrinolytic, and type of heparin.
Is aspirin plus dipyridamole superior to aspirin alone?
Aspirin Therapy Should Be First-Line Treatment in Secondary Prevention of Stroke—Against. Taken together, these study results show that the combination of aspirin plus dipyridamole is superior to aspirin alone in the prevention of stroke after TIA or stroke. The bleeding risk is not higher than with aspirin alone.
Does clopidogrel interact with Celebrex?
CLOPIDOGREL in Plavix may interact with CELECOXIB in Celebrex. Although the cause of this interaction is not understood, when clopidogrel is used together with celecoxib, the risk of bleeding may be increased. Usually, celecoxib is not recommended for use by people who are taking clopidogrel.
Does adding clopidogrel to aspirin reduce stroke risk?
Adding clopidogrel to aspirin has been associated with lower risk for stroke among patients with atrial fibrillation and those with acute coronary syndromes, but dual antiplatelet therapy has also been associated with increased bleeding.