Table of Contents
- 1 What is the meaning of physicochemical properties?
- 2 What is physicochemical effect?
- 3 Which of the following is a physicochemical property?
- 4 What are the reasons to consider physicochemical properties during drug design?
- 5 How do you write a physicochemical?
- 6 Which one of these is a physicochemical property of drug substance?
- 7 What does physiochemical mean?
- 8 What is physico-chemical theory?
What is the meaning of physicochemical properties?
Physico-chemical properties are the intrinsic physical and chemical characteristics of a substance. These include appearance, boiling point, density, volatility, water solubility and flammability etc.
What is physicochemical effect?
The physicochemical properties (size, shape, surface chemistry, porosity, elasticity, and many others) of these nanocarriers influence its biological identity, which in presence of biological barriers in vivo, could significantly modulate the therapeutic index of its cargo and alter the desired outcome.
What is the difference between physiochemical and physicochemical?
As adjectives the difference between physicochemical and physiochemical. is that physicochemical is dependent on the joint action of both physical and chemical processes while physiochemical is of or pertaining to both physiology and chemistry.
What are physicochemical drugs?
Psychochemical warfare involves the use of psychopharmacological agents (mind-altering drugs or chemicals) with the intention of incapacitating an adversary through the temporary induction of hallucinations or delirium.
Which of the following is a physicochemical property?
For example, the IC2 framework lists a variety of physicochemical properties that should be considered when assessing exposure pathways, including: volatility/vapor pressure, molecular weight and size, solubility, logP (as Kow), boiling point, melting point, density/specific gravity, pH, corrosivity, and dissociation …
What are the reasons to consider physicochemical properties during drug design?
Physicochemical properties underlie all aspects of drug action and are critical for solubility, permeability and successful formulation. Specific physicochemical properties shown to be relevant to oral drugs are size, lipophilicity, ionisation, hydrogen bonding, polarity, aromaticity and shape.
What are physicochemical properties examples?
How does physicochemical properties affect drug absorption?
The various physicochemical properties of drug that affect drug dissolution and its rate are—solubility, particle size, polymorphism, salt form, pseudopolymorphism, complexation, wettability, etc. Dosage form factors include several formulation factors and excipients incorporated in the dosage form.
How do you write a physicochemical?
physicochemical
- adjective phys·i·co·chem·i·cal \ˌfi.
- zi.
- kō
- ˈke.
- mi.
- kəl\. Definition of physicochemical . 1 : being physical and chemical.
- Understanding the physicochemical properties of a compound such as solubility, stability, form definition, solid.
- state properties, partition coefficient and …
Which one of these is a physicochemical property of drug substance?
Which one of these is a physicochemical property of Drug substance? Explanation: Physicochemical properties of drug substances include drug solubility, dissolution rate, particle size, effective surface area, polymorphism, etc. Dissolution time comes under Dosage form characteristics and pharmaceutic ingredients.
What is the importance of knowing the physicochemical properties of a drug?
Summary. A complete knowledge of the relevant therapeutic and physicochemical properties of the drug is required to determine the proper formulation and delivery method of a drug.
What is physicochemical properties that affect bioavailability?
The physicochemical properties of the drug that will influence its passage into solution and transfer across membranes include its dissolution rate, pKa, lipid solubility, chemical stability and complexation potential.
What does physiochemical mean?
Physicochemical (adj) involving the principles of both physics and chemistry; dependent on, or produced by, the joint action of physical and chemical agencies.
What is physico-chemical theory?
Physical chemistry is the study of macroscopic, and particulate phenomena in chemical systems in terms of the principles, practices, and concepts of physics such as motion, energy, force, time, thermodynamics, quantum chemistry, statistical mechanics, analytical dynamics and chemical equilibrium.. Physical chemistry, in contrast to chemical physics, is predominantly (but not always) a
What does physicochemical processes mean?
Physicochemical Processes. Physical reactions involved in the formation of or changes in the structure of atoms and molecules and their interactions.
What is physicochemical properties?
Physicochemical properties of the amino acids. The physicochemical properties of a protein are determined by the analogous properties of the amino acids in it. The α-carbon atom of all amino acids, with the exception of glycine , is asymmetric; this means that four different chemical entities (atoms or groups of atoms) are attached to it.