How accurate is alere?
After testing 120 samples from participants, the researchers found that the Alere HIV Combo Rapid Test had 91\% sensitivity and 100\% specificity for p24 antigen detection (Fitzgerald et al., 2016).
How early can Alere Determine detect HIV?
Timeframe for Alere Determine™ HIV-1/2 Ag/Ab Combo ONLY: Antigen can be detected 14-15 days after infection (Acute Infection). Antigen and antibodies can both be detected 21-28 days after infection (Early Infection).
Is an HIV DUO test conclusive after 28 days?
This HIV DUO test, including p24 antigen, is considered 99.8 percent accurate at 28 days. However, this accuracy increases to 99.9 percent at 90 days after potential contact.
How long does it take to detect HIV after exposure?
An antigen/antibody test performed by a laboratory on blood from a vein can usually detect HIV infection 18 to 45 days after an exposure. Antigen/ antibody tests done with blood from a finger prick can take longer to detect HIV (18 to 90 days after an exposure). Antibody tests can take 23 to 90 days to detect HIV infection after an exposure.
Can the Alere determine HIV test detect p24 antigen?
Most rapid tests, with the exception of the Alere HIV Combo and Alere Determine HIV-1/2 cannot detect p24 antigen. The accuracy of point-of-care tests is not always equal to those of laboratory tests, especially in relation to recent infection. This is for two main reasons:
How accurate are combination HIV antigen/antibody tests?
Combination HIV antigen/antibody tests are far more accurate than traditional antibody-based assays, particularly during the acute stage of infection. Lab-based tests still outperform at-site, point-of-care HIV tests, most especially in cases of recent HIV exposure.
How accurate are rapid point-of-care HIV tests?
How accurate are rapid, point-of-care tests for HIV? Rapid tests are usually reliable for long-standing infections, but are sometimes unable to detect recent HIV infections acquired in the past few weeks. Many tests are based on older ‘second-generation’ technology, but a ‘fourth-generation’ test with better performance is available.